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ATP is the currency system of the cell (like dollar bills). It fuels the work that cells need to do. While glucose is a simple sugar, it is still a relatively large molecule, therefore it needs certain transporters in order to allow it to enter a cell. These are known as GLUTs (glucose transporters). [2] Contrary to popular belief, not all cells require insulin in order to transport glucose inside of a cell. Some organs and tissues are insulin-independent, meaning insulin is not required, whereas others are insulin-dependent, meaning they require insulin. [3] GLUT 4 transporters are located on skeletal muscle, adipose tissue, and the heart and do require insulin. In order for glucose to be transported into these cells, insulin must bind to insulin receptors and signal for this process to occur. Insulin is produced by beta cells in the pancreas in response to high blood glucose levels. Once it is released, it binds to insulin receptors and triggers a response to allow glucose to be transported into the cell. [4]GLUT 1 Insulin independentBloodBlood-brain-barrierHeart (partially) GLUT 2Insulin-independentLiverPancreasSmall IntestineGLUT 3Insulin-independentBrain NeuronsSpermGLUT 4Insulin-dependentSkeletal MuscleAdipose tissue (fat)HeartDysfunctions in Glucose RegulationGlucose regulation can become dysfunctional at many different steps.
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Studies show that following a ketogenic diet is superior in inducing weight loss in patients with obesity. The induced weight loss is rapid, intense, and sustained until at least two years. [1]. While we’re focusing on short-term weight loss for this category, these findings of sustainment for ‘at least’ two years indicate that keto may also produce long-term results. Further, studies done studies done in obese men found significantly greater weight loss over a four-week period when subjects were allowed to eat “ad libitum” or as much as they wanted when they were eating keto vs a moderate carb diet (-6. 34 kg vs 4. 35 kg). [2] Additionally, a paper published in Nature found that subjects assigned to a “low calorie” (500 – 1000 calorie deficit) still didn’t lose as much weight as subjects on a ketogenic diet. After four months of eating a keto diet, 85% of subjects lost >10% of their body weight while only 17% in the low-calorie group accomplished the same. [3] Not to mention, their HA1C levels dropped by nearly a point in the ketogenic diet group which was significantly better than the low-calorie group, only in the same time period. These findings aren’t too surprising as the Standard American Diet (SAD) includes hundreds of high-glycemic, processed carbohydrates per day.
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Fill them with
your favorite egg-free breakfast bites
such as berries, sausage, smoked salmon bites, cucumber slices, and cream cheese.
